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Symbol
Name
ID

Kat6a
K(lysine) acetyltransferase 6A
MGI:2442415

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Human Phenotypes	Acute myeloid leukemia
Disease(s) Associated with KAT6A	Acute myeloid leukemia
acute myeloid leukemia

Mouse Phenotypes

abnormal thymus development

decreased thymus weight

small thymus

thymus hypoplasia

athymia

abnormal definitive hematopoiesis

decreased common myeloid progenitor cell number

absent common myeloid progenitor cells

abnormal erythropoiesis

abnormal B cell differentiation

decreased immature B cell number

decreased pro-B cell number

decreased double-negative T cell number

abnormal myelopoiesis

decreased bone marrow cell number

decreased erythroid progenitor cell number

increased nucleated erythrocyte cell number

decreased B cell number

decreased pre-B cell number

decreased hematopoietic stem cell number

abnormal hematopoietic stem cell morphology

decreased spleen weight

spleen hypoplasia

absent spleen

Availability

Mouse Genotype

Kat6a^tm1.1Glac/Kat6a^tm1.1Glac

Kat6a^tm1Avo/Kat6a^tm1Avo

Kat6a^tm1Iki/Kat6a^tm1Iki

Kat6a^tm2.2Avo/Kat6a^tm2.2Avo

Kat6a^tm1.1Glac/Kat6a⁺

Kat6a^tm1Avo/Kat6a⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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